In a preliminary cohort of children recovering from asymptomatic or mild coronavirus disease 2019, subclinical cardiac contractility alterations were associated with reduced regulatory T cells, shorter telomeres and elevated inflammatory markers 3 months post-infection. These findings suggest that immune dysregulation may contribute to silent post-coronavirus disease 2019 cardiac dysfunction and warrant confirmation in larger cohorts with long-term follow-up.
Di Chiara, C., Cantarutti, A., Sabatino, J., Sirico, D., Bonfante, F., Le Prevost, M., et al. (2026). Impaired Treg Response and Subclinical Cardiac Dysfunction in Children Following SARS-CoV-2 Infection. THE PEDIATRIC INFECTIOUS DISEASE JOURNAL, 45(7), 246-248 [10.1097/INF.0000000000005192].
Impaired Treg Response and Subclinical Cardiac Dysfunction in Children Following SARS-CoV-2 Infection
Cantarutti A.;
2026
Abstract
In a preliminary cohort of children recovering from asymptomatic or mild coronavirus disease 2019, subclinical cardiac contractility alterations were associated with reduced regulatory T cells, shorter telomeres and elevated inflammatory markers 3 months post-infection. These findings suggest that immune dysregulation may contribute to silent post-coronavirus disease 2019 cardiac dysfunction and warrant confirmation in larger cohorts with long-term follow-up.
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