Late fetal liver hematopoiesis was thought to primarily rely on hematopoietic stem cells (HSCs). Using new genetic-tracing tools, a study shows that EVI1-positive HSCs mainly undergo expansion in the fetal liver, while differentiated blood cell production depends on HSC-independent intermediate hematopoietic progenitors.
Azzoni, E., Fantin, A. (2022). Fetal liver hematopoiesis revisited: a precast hierarchy. NATURE CARDIOVASCULAR RESEARCH, 1(10), 872-873 [10.1038/s44161-022-00142-5].
Fetal liver hematopoiesis revisited: a precast hierarchy
Azzoni, Emanuele
;
2022
Abstract
Late fetal liver hematopoiesis was thought to primarily rely on hematopoietic stem cells (HSCs). Using new genetic-tracing tools, a study shows that EVI1-positive HSCs mainly undergo expansion in the fetal liver, while differentiated blood cell production depends on HSC-independent intermediate hematopoietic progenitors.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Azzoni-2022-Nature Cardiovasc Res-VoR.pdf
Solo gestori archivio
Tipologia di allegato:
Publisher’s Version (Version of Record, VoR)
Licenza:
Tutti i diritti riservati
Dimensione
1.24 MB
Formato
Adobe PDF
|
1.24 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
|
Azzoni-2022-Nature Cardiovasc Res-preprint.pdf
accesso aperto
Tipologia di allegato:
Submitted Version (Pre-print)
Licenza:
Creative Commons
Dimensione
312.96 kB
Formato
Adobe PDF
|
312.96 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
