Bicocca Open Archive

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LONGHESE, MARIA PIA
 Distribuzione geografica
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Continente #
NA - Nord America 14.194
EU - Europa 9.548
AS - Asia 6.572
SA - Sud America 818
AF - Africa 147
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 7
Totale 31.293
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Nazione #
US - Stati Uniti d'America 13.542
SE - Svezia 2.604
IT - Italia 2.199
SG - Singapore 2.027
CN - Cina 1.661
VN - Vietnam 1.014
DE - Germania 1.001
RU - Federazione Russa 785
HK - Hong Kong 777
PL - Polonia 639
BR - Brasile 620
CA - Canada 558
FR - Francia 429
GB - Regno Unito 407
IE - Irlanda 397
UA - Ucraina 345
IN - India 271
FI - Finlandia 153
AT - Austria 149
NL - Olanda 129
TR - Turchia 115
BD - Bangladesh 114
ID - Indonesia 105
DK - Danimarca 103
KR - Corea 97
IQ - Iraq 69
AR - Argentina 68
ZA - Sudafrica 60
MX - Messico 58
ES - Italia 51
CH - Svizzera 43
JP - Giappone 41
BE - Belgio 40
SA - Arabia Saudita 39
EC - Ecuador 38
PK - Pakistan 37
PH - Filippine 35
UZ - Uzbekistan 32
CO - Colombia 24
VE - Venezuela 23
AE - Emirati Arabi Uniti 16
MA - Marocco 16
EG - Egitto 15
AZ - Azerbaigian 14
OM - Oman 14
KZ - Kazakistan 12
CL - Cile 11
NP - Nepal 11
PE - Perù 11
JO - Giordania 10
KE - Kenya 10
MY - Malesia 10
IL - Israele 9
LT - Lituania 9
PY - Paraguay 9
UY - Uruguay 9
DO - Repubblica Dominicana 8
ET - Etiopia 8
RS - Serbia 8
TN - Tunisia 8
BG - Bulgaria 7
CZ - Repubblica Ceca 7
GR - Grecia 7
IR - Iran 7
PS - Palestinian Territory 7
AU - Australia 6
EU - Europa 6
JM - Giamaica 6
KG - Kirghizistan 6
DZ - Algeria 5
PT - Portogallo 5
RO - Romania 5
TT - Trinidad e Tobago 5
HN - Honduras 4
HU - Ungheria 4
SC - Seychelles 4
SK - Slovacchia (Repubblica Slovacca) 4
TH - Thailandia 4
TW - Taiwan 4
CR - Costa Rica 3
GT - Guatemala 3
HR - Croazia 3
MD - Moldavia 3
MU - Mauritius 3
PA - Panama 3
SN - Senegal 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
CI - Costa d'Avorio 2
CY - Cipro 2
GE - Georgia 2
GY - Guiana 2
KW - Kuwait 2
LV - Lettonia 2
LY - Libia 2
MN - Mongolia 2
NO - Norvegia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
Totale 31.267
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Città #
Ann Arbor 2.426
Stockholm 1.891
Ashburn 1.625
Singapore 1.217
Fairfield 933
Woodbridge 815
Milan 783
Hong Kong 757
Houston 668
Frankfurt am Main 660
Chandler 659
San Jose 657
Wilmington 605
Kraków 594
Dublin 382
Toronto 379
Seattle 374
Jacksonville 362
New York 312
Cambridge 278
Ho Chi Minh City 278
Dearborn 258
Los Angeles 248
Beijing 237
Santa Clara 235
Hanoi 193
Hefei 182
Princeton 164
Chicago 151
Dallas 148
Vienna 138
Dong Ket 128
Nanjing 117
The Dalles 116
Moscow 110
Council Bluffs 104
Shanghai 98
Altamura 92
Seoul 91
Buffalo 87
Lauterbourg 82
Lawrence 81
Jakarta 72
Guangzhou 68
San Diego 64
São Paulo 63
Rome 62
Helsinki 59
Boardman 55
Lachine 55
Fremont 54
Munich 53
London 50
Nanchang 48
Montreal 40
Brussels 39
Orem 39
Da Nang 38
Ottawa 38
Zurich 37
Johannesburg 35
Atlanta 32
Haiphong 32
Tokyo 30
Warsaw 30
Andover 29
Brooklyn 29
Hebei 29
New Delhi 28
Baghdad 27
Denver 27
Botticino 26
Changsha 26
Huizen 26
Jinan 26
Seveso 26
Tashkent 26
Chennai 25
Mexico City 23
Shenyang 23
Tianjin 23
Kunming 22
Poplar 21
Zhengzhou 21
Brescia 20
San Francisco 20
Amsterdam 19
Capralba 19
Falls Church 19
Mumbai 19
Philadelphia 19
Salt Lake City 19
Tampa 19
Turku 19
Biên Hòa 18
Manchester 18
Nuremberg 18
Cuggiono 17
Guayaquil 17
Brasília 16
Totale 21.587
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Nome #
Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation 1.928
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 585
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 556
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 555
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 533
The MRX complex regulates Exo1 resection activity by altering DNA end structure 529
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 516
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 501
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 470
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 464
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 456
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 451
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 449
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 432
Coupling end resection with the checkpoint response at DNA double-strand breaks 419
Functions and regulation of the MRX complex at DNA double-strand breaks 413
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 413
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 411
The regulation of the DNA damage response at telomeres: Focus on kinases 409
Regulation of telomere metabolism by the RNA processing protein Xrn1 401
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 399
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 395
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 388
Processing of DNA ends in the maintenance of genome stability 383
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 380
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 364
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 360
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 356
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends 355
How do cells sense DNA lesions? 352
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 349
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 346
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 342
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 341
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 334
Mechanisms and regulation of DNA end resection 333
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 331
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 329
Rif1 supports the function of the CST complex in yeast telomere capping 322
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 320
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 319
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 318
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 315
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 314
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 311
The cellular response to chromosome breakage 304
Telomeres and DNA damage checkpoints 303
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 303
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 299
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 294
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 290
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 287
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 287
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 286
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 284
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 282
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 282
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 281
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 281
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 279
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 279
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 279
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 278
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 276
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 274
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 272
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 271
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 270
Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FINGERS network) 269
RPA regulates telomerase action by providing Est1p access to chromosome ends 265
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 263
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 259
The DNA damage checkpoint: A tale from budding yeast 258
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 258
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 256
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 251
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 251
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 250
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 250
A central role for DNA replication forks in checkpoint activation and response 242
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 240
MRX-dependent DNA damage response to short telomeres 239
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 232
DNA damage response at functional and dysfunctional telomeres 231
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 223
The role of shelterin in maintaining telomere integrity 222
Telomere-end processing: mechanisms and regulation 218
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 217
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 211
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 208
Regulation of the DNA damage response by cyclin-dependent kinases 193
Checkpoint activation and recovery: regulation of the 9–1–1 axis by the PP2A phosphatase 184
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 181
Stn1 supports Mec1 function in protecting stalled replication forks from degradation 141
Totale 32.100
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Categoria #
all - tutte 86.553
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 86.553
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021523 0 0 0 0 0 0 0 0 0 0 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20253.724 185 327 245 173 265 169 261 134 269 769 339 588
2025/202611.402 1.053 662 692 1.208 1.206 542 1.381 506 836 2.766 550 0
Totale 32.100